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由于女性复发性膀胱炎的抗菌素单剂疗法能提高患者的遵医嘱程度,减少药物副作用,降低治疗代价和减少细菌耐药性,故受到医务人员的重视。然而对单剂量治疗非并发症性急性女性尿路感染的效果仍有争议。作者前瞻性地评价了女性患此症时用氟哌酸(Norfloxacin)单剂与三日治疗的效果及副作用。病人和方法选择年龄≥18岁的非并发症性下尿路感染的女性患者219例为研究对象。用随机双盲法将患者编入氟哌酸单剂量治疗组(112例)及三日治疗组(107例)。单剂量组患者首剂眼氟哌酸2片(每片400mg),以后每隔12小时服安慰剂1片,连续5次。三日组首剂服氟哌酸1片(400mg)及安慰剂1片,以后
Because of women’s recurrent cystitis antibiotic single-agent therapy can improve the degree of patient compliance, reduce drug side effects, reduce treatment costs and reduce bacterial resistance, it is the medical staff attention. However, the effect of a single dose on the treatment of urinary tract infections in non-complicating acute women remains controversial. The authors prospectively evaluated the efficacy and side effects of a single dose of Norfloxacin and a three-day treatment for women with this condition. 219 patients with non-complication lower urinary tract infection who were ≥18 years old and whose methods were selected as the research object. The patients were enrolled in a single dose of norfloxacin group (n = 112) and a three-day treatment group (n = 107) by a randomized double-blind method. In the single-dose group, the first dose of norfloxacin (2 tablets per tablet) (400 mg per tablet), followed by placebo 1 tablet every 12 hours for 5 consecutive times. The first day of the third group of norfloxacin 1 (400mg) and placebo 1, after