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目的:比较银杏达莫注射液与复方丹参注射液治疗急性脑梗死的疗效。方法:分析2013年1月-2015年1月我院收治的急性脑梗死患者90例的临床资料,随机分为对照组和观察组各45例,对照组给予复方丹参注射液治疗,观察组给予银杏达莫注射液治疗,比较两组的各项指标,临床疗效及不良反应。结果:美国国立卫生院脑卒中量表(NIHSS)评分结果显示,治疗后7 d、14 d,两组的NIHSS评分显著低于治疗前,差异具有统计学意义(P<0.05);治疗后7 d、14 d,观察组明显比对照组更低,差异具有统计学意义(P<0.05)。观察组总有效率88.89%明显优于对照组的75.56%,组间比较,差异具有统计学意义(P<0.05)。治疗后两组的全血液黏稠度(高切、低切)、血浆黏度和纤维蛋白原与治疗前相互对应比较,差异具有统计学意义(P<0.05);治疗后,观察组在上述指标与对照组比较,差异具有统计学意义(P<0.05)。结论:银杏达莫注射液治疗急性脑梗死疗效显著,有助于患者神经功能恢复,能有效的降低血液黏度,能起到改善血液流变学状态的作用。
Objective: To compare the curative effect of ginkgo-damo injection and compound salvia miltiorrhiza injection on acute cerebral infarction. Methods: The clinical data of 90 patients with acute cerebral infarction admitted to our hospital from January 2013 to January 2015 were randomly divided into control group and observation group (n = 45). The control group was given Fufang Danshen injection and the observation group was given Ginkgo bamo Injection treatment, the two groups of indicators, clinical efficacy and adverse reactions. Results: The National Institutes of Health Stroke Scale (NIHSS) score showed that on the 7th and 14th day after treatment, the NIHSS scores of the two groups were significantly lower than those before treatment (P <0.05); after 7 At 14 days, the observation group was significantly lower than that of the control group, with statistical significance (P <0.05). The total effective rate in observation group was 88.89%, which was significantly better than that in control group (75.56%). There was significant difference between two groups (P <0.05). After treatment, the whole blood viscosity (high-cut, low-cut), plasma viscosity and fibrinogen of the two groups were compared with each other before treatment, the difference was statistically significant (P <0.05); after treatment, The difference between the two groups was statistically significant (P <0.05). Conclusion: The effect of Yinxingdamo injection in the treatment of acute cerebral infarction is significant, which can help patients to recover neurological function, reduce blood viscosity effectively and improve the hemorheological status.