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目的:观察双氯灭痛滴眼剂在白内障手术中的抗炎作用。方法:25例(26眼)预接受白内障囊外摘除+人工晶体植入术患者随机分为治疗组(14眼)和对照组(12眼),对照组术前常规用药;治疗组除常规给药外,另手术前一天给予1%双氯灭痛滴眼4次,术前1h内加滴3次。结果:双氯灭痛治疗组瞳孔平均直径在娩核前(841±041mm)及灌洗后(784±059mm)均大于对照组(分别为783±061mm和708±073mm)(P<001),术后角膜水肿评分均值(107±048)低于对照眼(175±087)(P<005)。结论:01%双氯灭痛滴眼剂对白内障术中缩瞳反应及术后炎症具有明显抑制作用。
Objective: To observe the anti-inflammatory effect of diclofenac eye drops in cataract surgery. Methods: Twenty-five eyes (26 eyes) underwent extracapsular cataract extraction combined with intraocular lens implantation were randomly divided into treatment group (14 eyes) and control group (12 eyes) In addition, the other day before surgery to give 1% diclofenac 4 hours, plus 1h before surgery drops 3 times. Results: The mean pupil diameter of diclofenac group was significantly higher than that of control group (841 ± 041mm) and lavage (784 ± 059mm) (783 ± 061mm and 7 08 ± 073mm) (P <001), and the mean corneal edema score after operation (107 ± 048) was lower than that of the control eye (175 ± 087) (P005) . Conclusion: 01% diclofenac eye drops have a significant inhibitory effect on the miosis response and inflammation after cataract surgery.