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目的 :观察HP感染对胃粘膜上皮ICAM 1的影响。方法 :采用免疫组化方法对 47例HP感染阳性和 41例HP感染阴性患者的胃粘膜上皮细胞膜ICAM 1表达进行研究。结果 :HP感染阳性者ICAM 1表达增高 ,且与HP感染阴性者比较有显著性差异 (P <0 .0 5 )。结论 :HP感染促进胃粘膜上皮ICAM 1表达升高。
Objective: To observe the effect of HP infection on gastric mucosal epithelium ICAM 1. Methods: Immunohistochemistry was used to study the expression of ICAM-1 in 47 cases of HP-positive and 41 cases of HP-negative gastric mucosal epithelial cells. Results: The positive expression of ICAM 1 in HP infection was significantly higher than that in HP infection (P <0.05). Conclusion: HP infection can promote the expression of ICAM 1 in gastric mucosa epithelium.