内脏利什曼病时肠部损害被认为系继发性感染。本文报道一例空肠粘膜出现利杜体浸润的病例,而文献中尚未有类似报告。患者男性,54岁,印度人。发热已3月,有纳差,体重下降及腹泻。曾因结核样麻疯而用氨苯砜已5年,但入院前已2wk未用药。体检肝、脾肿大,血红蛋白9.0g/dl,白细胞计数4000/mm~2。血小板数正常,血沉140mm/头1h。总蛋白10.2g/dl,自蛋白3.0/dl,球蛋白7.2/dl。肠胃内镜检仅有轻度胃窦炎及糜烂性十二指肠炎。3天大便脂肪检查及D-木糖吸收试验表明无吸收不良。为排除淋巴瘤或其他血液系统恶性肿瘤作骨穿及空肠 Intestinal leishmaniasis intestinal damage is considered secondary infection. This article reports a case of jejunal mucosal leakage of lentigo body, and the literature has not been a similar report. Male patient, 54 years old, Indian. Fever has been in March, with anorexia, weight loss and diarrhea. Have used dapsone because of tuberculosis-like leprosy has been 5 years, but before admission 2wk not medication. Physical examination of liver, splenomegaly, hemoglobin 9.0g / dl, white blood cell count 4000 / mm ~ 2. Normal platelet count, ESR 140mm / head 1h. Total protein 10.2g / dl, since the protein 3.0 / dl, globulin 7.2 / dl. Gastrointestinal endoscopy only mild gastritis and erosive duodenitis. 3 days stool fat examination and D-xylose absorption test showed no malabsorption. For the exclusion of lymphoma or other hematological malignancies for bone wear and jejunum