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目的:探讨西咪替丁联合复方甘草酸苷治疗小儿过敏性紫癜的临床效果。方法:选取2010年1月至2014年1月期间接受治疗的小儿过敏性紫癜患者150例,随机将其分为观察组与对照组,每组75例。对照组患者进行传统治疗,观察组患者在此基础上以西咪替丁联合复方甘草酸苷进行治疗,对两组患者的治疗效果进行对比。结果:观察组和对照组患者的治疗有效率分别为94.6%与80.0%,观察组患者的治疗效果明显高于对照组患者,组间相比差异具有统计学意义(P<0.05)。结论:西咪替丁联合复方甘草酸苷治疗小儿过敏性紫癜具有显著的临床效果和较高的安全性,值得临床推广。
Objective: To investigate the clinical effect of cimetidine combined with compound glycyrrhizin in the treatment of Henoch-Schonlein purpura in children. Methods: 150 cases of children with Henoch-Schonlein purpura treated from January 2010 to January 2014 were randomly divided into observation group and control group, with 75 cases in each group. The patients in the control group were treated by traditional therapy. The patients in the observation group were treated with cimetidine combined with compound glycyrrhizin on the basis of this study, and the treatment effect was compared between the two groups. Results: The effective rates of treatment in observation group and control group were 94.6% and 80.0% respectively. The treatment effect in observation group was significantly higher than that in control group. There was significant difference between two groups (P <0.05). Conclusion: Cimetidine combined with compound glycyrrhizin in children with Henoch-Schonlein Purpura has significant clinical effect and high safety, which is worthy of clinical promotion.