目的:探讨经肛巨结肠根治术在新生儿巨结肠治疗中应用的可行性和疗效。方法:对10年来264例先天性巨结肠症新生儿进行钡剂灌肠或吸吮法直肠黏膜活检术术前诊断,用Torre手术巨结肠根治术式进行治疗并对其治疗结果进行分析。结果:264例平均手术时间35 min(18～70 min),平均出血7 ml(5～10 ml);随访1～8年,症状复发23例,肛门狭窄13例,大便污粪3例,肛门直肠黏膜脱垂15例。以上复发病例均经二次手术治愈,死亡5例。结论:经肛巨结肠根治手术使大部分新生儿期的巨结肠手术一期根治成为可能并效果满意,值得大力推广。 Objective: To investigate the feasibility and efficacy of transanal Hirschsprung’s disease in neonatal Hirschsprung’s disease. Methods: 264 cases of Hirschsprung’s disease in 10 years were diagnosed preoperatively with barium enema or sucking mucosal biopsy, and then treated with Torre Hirschsprung radical surgery and the treatment results were analyzed. Results: The mean operation time was 264 min (35 min, 18-70 min) and average bleeding was 7 ml (5-10 ml). The patients were followed up for 1 to 8 years with 23 cases of recurrent symptoms, 13 cases of anus stenosis, 3 cases of stool excrement, Rectal mucosal prolapse in 15 cases. The recurrence of the above cases were cured by the second surgery, 5 patients died. CONCLUSIONS: Hirschsprung’s radical surgery makes most of the neonatal Hirschsprung’s surgery possible and effective, and is worth promoting.