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目的探讨阿奇霉素联合氨茶碱治疗变异性哮喘的临床疗效。方法选取我院收治的变异性哮喘患者84例,按照随机数字表分为治疗组44例和对照组40例。对照组口服氨茶碱,同时服用舒喘灵或酮替芬等治疗;治疗组在对照组基础上加用阿奇霉素,于治疗后评价患者的治疗效果。结果两组患者临床症状均较治疗前有改善,对照组与治疗组相比,症状改善明显,二者有统计学差异(P<0.05);治疗后治疗组的总有效率为93.2%,与对照组相比(72.5%)相比,差异有统计学意义(P<0.01)。结论阿奇霉素联合氨茶碱治疗变异性哮喘治疗效果明显,有临床推广的价值。
Objective To investigate the clinical efficacy of azithromycin combined with aminophylline in the treatment of variant asthma. Methods Eighty-four patients with variant asthma admitted to our hospital were divided into treatment group (n = 44) and control group (n = 40) according to random number table. The control group oral aminophylline, while taking salbutamol or ketotifen treatment; treatment group in the control group based on the addition of azithromycin, after treatment to evaluate the therapeutic effect of patients. Results The clinical symptoms of both groups were improved compared with those before treatment. The symptoms in the control group and the treatment group were significantly improved (P <0.05), and the total effective rate was 93.2% in the treatment group Compared with the control group (72.5%), the difference was statistically significant (P <0.01). Conclusion Azithromycin combined with aminophylline treatment of variant asthma treatment effect is obvious, the value of clinical promotion.