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交感神经的功能低下似乎通过某种机制影响到副交感系统,为了评价因长期用利血平治疗引起的鼻粘膜内交感神经系功能低下,是否影响鼻粘膜内受体水平的副交感系统,作者用已由利血平处理造成化学性去交感神经支配的豚鼠鼻粘膜作了受体结合测定。实验动物用17只雄豚鼠:1组6只,用0.1mg/只利血平腹膜内注射每日一次共4周;2组11只,用生理盐水腹膜内注射每日一次共4周作为对照。结束后3周均放血处死取鼻粘膜供检验。结果利血平处理组的鼻粘膜内蕈毒碱性受体结合于二奎
Sympathetic dysfunction seems to affect the parasympathetic system through some mechanism. In order to evaluate whether the sympathetic nervous system in the nasal mucosa caused by long-term treatment with reserpine affects the parasympathetic system that affects the level of the receptor in the nasal mucosa, Receptor binding assays were performed on the nasal mucosa of guinea pigs that led to chemical de-sympathetic administration by reserpine treatment. Seven male guinea pigs were used in the experimental animals: six rats in group 1 were injected intraperitoneally with 0.1 mg / reserpine for 4 weeks; and two rats in group 11 were injected intraperitoneally with saline for 4 weeks once a day for control. 3 weeks after the end of bleeding were sacrificed nasal mucosa for testing. Results: The nasal mucosal muscarinic receptors in the nasal mucosa of reserpine treatment group were bound to Ergui