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目的观察他巴唑与放射性131碘(~(131)Ⅰ)长期治疗甲状腺功能亢进(甲亢)的效果。方法选取医院接诊的甲状腺功能亢进患者80例,随机分为研究组和对照组各40例,对照组实施他巴唑治疗,研究组实施放射性~(131)Ⅰ治疗,均为长期治疗,均随访1年以上,对比2组临床效果、甲状腺功能降低(甲减)发生率及随访1年复发率。结果研究组总有效率为92.50%明显高于对照组的75.00%,差异有统计学意义(P<0.05);研究组甲减发生率与随访复发率均明显低于对照组,差异有统计学意义(P<0.05)。结论甲亢患者采取他巴唑与放射性~(131)Ⅰ治疗均有一定效果,但相比而言,放射性~(131)Ⅰ治疗疗效更优,同时安全性更高,长期治疗复发率较低,值得借鉴。
Objective To observe the effect of long-term treatment of hyperthyroidism (hyperthyroidism) with methimazole and radioactive 131 iodine (~ (131) Ⅰ). Methods Eighty patients with hyperthyroidism admitted to hospital were randomly divided into study group (40 cases) and control group (40 cases). The control group was treated with methimazole and the study group was treated with radioactive 131 Ⅰ therapy, both of which were long-term treatment Follow-up more than 1 year, the clinical efficacy of two groups were compared, the incidence of hypothyroidism (hypothyroidism) and follow-up of 1 year recurrence rate. Results The total effective rate of study group was 92.50%, which was significantly higher than that of control group (75.00%), the difference was statistically significant (P <0.05). The incidence of hypothyroidism and follow-up of study group were significantly lower than that of control group Significance (P <0.05). Conclusions In patients with hyperthyroidism, both methimazole and radioactive 131I treatment have some effect, but in comparison, radioactive 131I treatment has better effect, higher safety and lower recurrence rate in long term, Worth learning.