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本实验采用改良纸片相邻法，以头孢西丁为诱导剂，头孢哌酮和头孢噻甲羧肟分别为靶β-内酰胺药物。检测1996年7月～1997年3月临床分离出的193株常见革兰阴性杆菌诱导型β-内酰胺酶的情况。发现有81菌株42％（81／193）出现诱导型β-内酰胺酶（即所谓的截平现象），其中能达到Sander判定为诱导株标准的有24株菌，占12．4％。临床常见革兰阴性杆菌中易产生诱导性肝内酸胶酶以阴沟肠杆菌、黄杆菌、铜绿假单胞菌多见。利用诱导剂一靶β-内酰胺药物的纸片相邻法与革兰阴性菌的日常药敏的有机结合，可使临床实验室在报告药敏结果同时予以报告产诱导酶的情况，以供临床用药时参考。
In this experiment, the improved method of paper adjacent to cefoxitin as an inducer, cefoperazone and ceftazidime respectively target β-lactam drugs. 193 cases of common Gram-negative bacilli-induced β-lactamase were isolated from July 1996 to March 1997. In 81 strains, 42% (81/193) of the isolates showed inducible β-lactamases (the so-called truncation phenomenon). Among them, 24 strains (12.4%) were found to be Sander’s standard of inducing strain. Common gram-negative bacilli in clinical prone to produce induced intrahepatic gel enzyme Enterobacter cloacae, Flavobacterium, Pseudomonas aeruginosa more common. The combination of an inducer, a target β-lactam drug, and the daily drug susceptibility of gram-negative bacteria allows clinical laboratories to report drug susceptibility results while inducing enzyme production for Clinical medication reference.