论文部分内容阅读
[目的]了解福州市麻疹流行特征,评价抗体水平,为防控措施提供科学依据。[方法]根据常规传染病报告系统,对2007年麻疹流行特征进行分析,采用ELISA法对样本进行检测。[结果]2007年麻疹发病率为9.599/10万,全年无疫情暴发。仓山、晋安等城乡结合区发病率较高,0~14岁为高发年龄段,3~8月为高发季节。病例中流动人口占50.7%,无免疫史占54.6%。抗体水平监测显示,流动人群、本地人群和孕妇的麻疹抗体阳性率类似,几何平均滴度(GMT)的差异显著。不同年龄组和不同免疫史人群抗体阳性率和GMT类似。县城的本地和流动人群抗体阳性率均高于市区;市区及县城流动人群抗体阳性率高于本地人群。市区和县城、本地人群和流动人群的GMT类似。[结论]加强麻疹常规免疫管理工作,提高接种率,适时调整免疫策略,对重点地区、重点人群加强免疫和监测,是有效控制和消除麻疹的关键。
[Objective] To understand the epidemic characteristics of measles in Fuzhou, evaluate antibody levels and provide a scientific basis for prevention and control measures. [Method] Based on the conventional infectious disease reporting system, the epidemiological characteristics of measles in 2007 were analyzed and the samples were tested by ELISA. [Results] The incidence of measles in 2007 was 9.599 / 100 000, with no epidemic outbreak throughout the year. Cangshan, Jinan and other urban and rural areas with a higher incidence, 0 to 14 years of age for the high incidence of 3 to 8 months for the high season. The floating population accounted for 50.7% of cases, no history of immunization accounted for 54.6%. Antibody level monitoring showed that measles antibody positive rates were similar in migrants, locals and pregnant women, with significant differences in geometric mean titer (GMT). The antibody positive rate in different age groups and different immunization history was similar to GMT. The positive rate of antibody in local and floating population in county seat was higher than that in urban area; the positive rate of antibody in floating population in urban area and county seat was higher than that of local population. The urban areas and the county seat, local people and migrants have similar GMTs. [Conclusion] The key to effective control and elimination of measles is to strengthen routine immunization management of measles, increase inoculation rate, adjust immunization strategy in time and strengthen immunization and monitoring in key areas and key populations.