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肝乐口服液是湖北省中医院制剂中心生产的医院制剂,由白花蛇舌草、赤芍、黄芪等中药制备而成,具有益气养肝之功效,用于治疗病毒性肝炎。方中君药白花蛇舌草含有多糖、三萜酸、黄酮类、蒽醌类等多种化合物[1],齐墩果酸和熊果酸是其含有的两个主要有效成分,其中齐墩果酸具有很好地保护肝脏、利水渗湿等功效;为了控制该产品的质量,我们采用高效液相色谱法测定了肝乐口服液中齐墩果酸的含量。1仪器与试药LC-10A型高效液相色谱仪、AUW120D电子天平(日本岛
Liver Lok Oral Liquid is produced in Hubei Province Hospital Preparation Center Hospital preparations, from the Hedyotis diffusa, Radix Paeoniae Rubra and other traditional Chinese medicine prepared with Qi and Liver for the efficacy of the treatment of viral hepatitis. Fangzhong Jun Hedyotis diffusa contains polysaccharides, triterpenic acid, flavonoids, anthraquinones and other compounds [1], oleanolic acid and ursolic acid are the two main active ingredients which oleanolic acid With good protection of the liver, diuresis and other effects of water; in order to control the quality of the product, we used high performance liquid chromatography determination of liver oleanolic oleanolic acid content. 1 instruments and reagents LC-10A high performance liquid chromatography, AUW120D electronic balance (Japan Island