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鼻咽癌主要为非角化鳞状细胞癌,其恶性程度很高,伴随着局部浸润和早期远处转移。鼻咽癌的病因主要包括3个方面,即遗传易感性、环境因素和EB病毒(EBV)感染,然而,鼻咽癌发病的分子机制仍未完全明确。鼻咽癌对放化疗非常敏感,如果肿瘤仅局限于鼻咽部,可以通过放疗治愈。遗憾的是,30%~40%确诊的患者已经到了晚期,他们往往在治疗4年后
Nasopharyngeal carcinoma is mainly non-keratinizing squamous cell carcinoma, with a high degree of malignancy, with local infiltration and early distant metastasis. The causes of NPC mainly include three aspects: genetic susceptibility, environmental factors and Epstein-Barr virus (EBV) infection. However, the molecular mechanism of NPC is still not fully understood. Nasopharyngeal carcinoma is very sensitive to radiotherapy and chemotherapy, if the tumor is confined to the nasopharynx, can be cured by radiotherapy. Unfortunately, 30% to 40% of the patients who have been diagnosed have reached an advanced stage and are often treated 4 years later