论文部分内容阅读
目的探讨胃癌病理分型及其治疗情况。方法回顾性分析100例胃癌患者的病理资料和临床治疗情况。结果 100例胃癌患者中腺癌84例、印戒细胞癌9例、其他及分型不详7例;TNM分期0期1例、Ⅰ期3例、Ⅱ期11例、Ⅲ期68例、Ⅳ期17例。腺癌分化程度及TNM分期不同的胃癌患者中位总生存期比较差异有统计学意义(P<0.01)。病理类型及腺癌分化程度不同的Ⅳ期患者中位总生存期比较差异有统计学意义(P<0.05)。行不同手术方式治疗的胃癌患者中位总生存期比较差异有统计学意义(P<0.05)。术后行辅助化疗与未辅助化疗的胃癌患者中位无病生存期比较差异有统计学意义(P<0.05)。结论不同病理类型及治疗方案均影响胃癌患者预后,外科手术结合辅助化疗的综合治疗可改善患者预后。
Objective To explore the pathological classification and treatment of gastric cancer. Methods The pathological data and clinical treatment of 100 patients with gastric cancer were retrospectively analyzed. Results There were 84 cases of adenocarcinoma, 9 cases of signet ring cell carcinoma, and 7 cases of signet ring cell carcinoma in other 100 cases of gastric cancer. There were 1 case in stage 0, 3 cases in stage I, 11 cases in stage II, 68 cases in stage III, stage IV in TNM stage. 17 cases. The median overall survival of patients with different grades of adenocarcinoma differentiation and TNM staging was significantly different (P<0.01). The median overall survival of patients with stage IV and different degrees of adenocarcinoma differentiation was statistically significant (P<0.05). The median overall survival of gastric cancer patients treated with different surgical methods was statistically significant (P<0.05). The median disease-free survival of patients with adjuvant chemotherapy and unadjuvant chemotherapy was statistically significant (P<0.05). Conclusion Different pathological types and treatment options affect the prognosis of gastric cancer patients. Comprehensive treatment combined with adjuvant chemotherapy can improve the prognosis of patients.