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麝香Musk是一个动物性的生药。在中国和印度麝香的疗效主要在于抗炎症。而测定天然麝香抗炎作用的方法较多。例如:Mishra,R.K.等人报导的方法,由高木等人改进的Whittle法,Sorkin将Boyden法改为的体外法,以及大白鼠滤纸丸法。但这些实验的方法都不适宜于贵重的天然麝香抗炎成份的药理筛选。我们学习了中国医学科学院北京药物研究所用小白鼠——巴豆油涂耳刺激法进行了大批地筛选天然麝香水溶性抗炎成份的经验,采用小白鼠——巴豆油涂耳刺激法进行了天然麝香及其醚溶性部分抗炎作用的药理研究,获得了较为满意的结果,现介绍如下:
Musk Musk is an animal crude drug. The curative effect of musk in China and India is mainly anti-inflammatory. There are many ways to measure the anti-inflammatory effects of natural musk. For example, the method reported by Mishra, R.K., et al., the Whittle method modified by Takagi et al., the in vitro method modified by Sorkin’s Boyden method, and the rat filter paper method. However, these experimental methods are not suitable for the pharmacological screening of valuable natural musk anti-inflammatory ingredients. We learned from the Beijing Institute of Materia Medica, Chinese Academy of Medical Sciences, using a white mouse, croton oil ear-stimulating method, to conduct a large number of screenings of natural musk water-soluble anti-inflammatory ingredients. The musk mouse was applied to stimulate the natural musk. The pharmacological research on the anti-inflammatory effects of its ether-soluble part has obtained satisfactory results. Now it is introduced as follows: