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目的:了解不同血β-HCG浓度宫外孕采用药物米非司酮联合甲氨蝶呤保守治疗的临床效果。方法:随机选取98例宫外孕住院患者作本次调查对象,给予米非司酮联合甲氨蝶呤治疗,并根据不同血β-HCG浓度进行分组,1000U/L<血β-HCG浓度≤2000U/L为研究组,血β-HCG浓度>2000U/L为对照组,对比两组患者最终治疗情况。结果:研究组1000U/L<血β-HCG浓度≤2000U/L宫外孕患者通过采用药物米非司酮联合甲氨蝶呤保守治疗后治愈率为95.91%、失败率为4.08%;对照组血β-HCG浓度>2000U/L宫外孕患者通过相同药物保守治疗后治愈率为79.59%、失败率为20.4%,两组不同血β-HCG浓度宫外孕患者均采用同种药物相同剂量治疗,治愈结果比较差异显著(P<0.05)。结论:宫外孕可采用药物保守治疗,在血β-HCG浓度<2000U/L时用药疗效更佳。
OBJECTIVE: To investigate the clinical effect of conservative treatment with mifepristone and methotrexate in patients with different concentrations of blood β-HCG. Methods: A total of 98 inpatients with ectopic pregnancy were randomly selected to receive mifepristone combined with methotrexate. The patients were divided into groups according to different concentrations of β-HCG. The concentration of 1000U / L was ≤2000U / L for the study group, serum β-HCG concentration> 2000U / L as the control group, compared the final treatment of two groups of patients. Results: The study group 1000U / L 2000U / L patients with ectopic pregnancy after conservative treatment by the same drug cure rate was 79.59%, the failure rate was 20.4%, two groups of different blood β-HCG concentrations of ectopic pregnancy were treated with the same dose of the same drug, the cure was significantly different Significant (P <0.05). Conclusion: Ectopic pregnancy can be conservative treatment of drugs, the blood β-HCG concentration <2000U / L when the medication better.