红霉素与地高辛均有胃肠道副作用,然而红霉素可使少数患者的地高辛浓度增加1倍,并可能将胃肠道副作用错误地旧因于红霉素。本文报道1例应用红霉素过程中引起地高辛中毒,出现心脏及胃肠道反应。病例报告患者女性,59岁,因上呼吸道感染服用红霉素,500mg tid,4天后出现恶心呕吐,持续2天,并有心动过缓。患者自1972年行二尖瓣置换术后一直应用维持量地 Erythromycin and digoxin have gastrointestinal side effects, however, erythromycin can make a small number of patients with digoxin concentrations doubled, and may be the wrong gastrointestinal side effects due to erythromycin. This article reports 1 case of erythromycin in the process of digoxin poisoning, heart and gastrointestinal reactions. Case Report Female patient, 59 years old, taking erythromycin 500 mg tid for upper respiratory tract infection and nausea and vomiting 4 days later, with sustained bradycardia. Patients have been using maintenance after mitral valve replacement since 1972