论文部分内容阅读
我国人口数量庞大,且随着经济发展和人民生活水平的不断提高及人口老龄化的趋势,原发性高血压的患者数量呈现逐年上升的趋势,而肾脏是高血压造成相关损害的重要靶器官之一,其中超过40%的高血压患者有肾脏受累,20%的高血压患者死于肾衰竭。因此,对高血压肾损伤机制的研究就显得尤为重要。高血压肾损伤的机制众多,早期报道肾入球小动脉的狭窄被认为是肾纤维化的首要原因,剩余的肾单位代偿性地增加肾
With the huge population in our country, with the continuous development of economy and people’s living standards and the aging population, the number of patients with essential hypertension is increasing year by year. The kidney is an important target organ for hypertension-related damage Among them, more than 40% of hypertensive patients have kidney involvement and 20% of hypertensive patients die of kidney failure. Therefore, the study of hypertensive renal injury mechanism is particularly important. Many mechanisms of hypertensive renal injury, early reports of renal artery stenosis is considered the primary cause of renal fibrosis, the remaining nephrons compensatory increase in the kidney