论文部分内容阅读
目的观察天花粉蛋白注射液保守治疗植入性胎盘的疗效及副反应。方法选择2006年1月至2012年6月自然分娩或剖宫产发现植入性胎盘适合保守治疗患者96例,随机分为观察组和对照组各48例。观察组采用天花粉蛋白注射液治疗,对照组采用甲氨蝶呤治疗,比较观察2组的临床疗效及副反应。结果观察组排出胎盘时间及阴道流血持续时间、血β-HCG下降时间、平均住院时间与对照组比较,差异均有统计学意义(P均<0.05),治疗成功率差异无统计学意义(P>0.05),副反应发生率比较差异有统计学意义(P<0.05)。结论天花粉蛋白注射液和甲氨蝶呤均能保守治疗植入性胎盘,但前者疗效快、住院时间少、副反应小。
Objective To observe the efficacy and side effects of trichosanthin injection in conservative treatment of placenta accreta. Methods From January 2006 to June 2012, 96 patients with conservative placenta accreta were treated by spontaneous labor or cesarean section, and randomly divided into observation group and control group, 48 cases each. The observation group was treated with trichosanthin injection, while the control group was treated with methotrexate. The clinical effects and side effects of the two groups were observed. Results The placenta discharge time, duration of vaginal bleeding, blood β-HCG declining time and average length of hospital stay in the observation group were significantly different from those in the control group (all P <0.05), and there was no significant difference in the success rate of treatment (P > 0.05), the incidence of side effects was significantly different (P <0.05). Conclusion Trichosanthin injection and methotrexate can conservative treatment of implanted placenta, but the former fast response, less hospital stay, fewer side effects.