口腔粘膜多发性淀粉样变在临床上较为少见。现报道如下：患者，男，58岁。主诉：口腔肿物二月余。病史：两个月前发现舌、颊部长肿物，逐渐增大，无溃烂及出血，无疼痛及搔痒感。8个月前因面色苍白在当地县医院诊断为“贫血”，经用各种药物治疗和牌切除、胃大部分切除等治疗， Oral mucosal multiple amyloidosis is clinically rare. Are reported as follows: Patients, male, 58 years old. Chief complaint: oral tumor in February more than. History: Two months ago found tongue, cheek long tumor, and gradually increased, no ulceration and bleeding, no pain and itching. 8 months ago because of pale in the local county hospital diagnosed as “anemia”, after a variety of drug treatment and licensing resection, stomach resection and other treatment,