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人体的T-淋巴细胞、特异抗体、巨噬细胞和/或组织细胞参与对肿瘤的免疫反应。郎格罕氏细胞为一种特殊类型的组织细胞,见于皮肤,也见于食管上皮、扁桃体、鼻咽上皮和淋巴组织,在皮肤细胞免疫中起重要作用。由于此细胞和T-淋巴细胞关系密切,也位于淋巴组织的T-带中,故也称之为T-带组织细胞(Tzone histiocytes)。在致密浸润型肺癌中已发现郎格罕氏细胞。鼻咽癌中是否也有此细胞?其多少是否和预后有关?为回答上述问题,作者用免疫组织化学方法,用S-100蛋白抗体和溶菌酶抗体对鼻咽癌的T-带组织细胞和巨噬细胞的分布进行了研究,并以正常人作对照。共获得49个鼻咽癌标本,原发肿瘤部位的标本40个,转移淋巴结标本9个。放疗后的病人除
Human T-lymphocytes, specific antibodies, macrophages and / or tissue cells are involved in the immune response to the tumor. Langerhans cell is a special type of tissue cells found in the skin, also found in the esophageal epithelium, tonsils, nasopharyngeal epithelium and lymphoid tissue, play an important role in skin cell immunity. Since this cell is also closely related to T-lymphocytes and is also located in the T-band of lymphoid tissue, it is also called Tzone histiocytes. Langerhans cells have been found in dense infiltrating lung cancers. Whether the number of nasopharyngeal carcinoma also has this cell? The number is related to the prognosis? In response to the above questions, the authors used immunohistochemistry, S-100 protein antibody and lysozyme antibody on nasopharyngeal carcinoma T-band cells and giant The distribution of the macrophages was studied and normal controls were used. A total of 49 specimens of nasopharyngeal carcinoma were obtained, 40 specimens of primary tumor and 9 specimens of metastatic lymph nodes. In addition to patients after radiotherapy