论文部分内容阅读
目的分析颅内动脉瘤破裂患者行介入栓塞术后并发急性脑积水的独立危险及保护因素。方法以98例颅内动脉瘤破裂、行介入栓塞术后并发急性脑积水患者为观察组,随机纳入同期入院术后未出现急性脑积水患者98例为对照组。统计其性别、年龄、吸烟史、饮酒史、高血压病病史、Hunt-Hess分级、动脉瘤位置、脑室积血、早期腰池引流情况。行Pearson单因素检验、Logistic多因素回归分析,确定急性脑积水独立影响因素。结果单因素分析指出:Hunt-Hess分级、脑室积血、早期腰池引流与急性脑积水显著相关(P<0.05);多因素回归分析指出:Hunt-Hess分级为术后急性脑积水独立危险因素(偏回归系数2.677,OR=14.542,95%CI=1.208~41.31)、早期腰池引流为术后急性脑积水独立保护因素(偏回归系数-3.201,OR=0.041,95%CI=0.003~0.412)。结论 Hunt-Hess分级为颅内动脉瘤破裂结束栓塞术后急性脑积水的独立危险因素,行早期腰池引流则有助于预防急性脑积水。
Objective To analyze the independent risk and protective factors of acute hydrocephalus after interventional embolization in patients with ruptured intracranial aneurysms. Methods A total of 98 patients with ruptured intracranial aneurysms were enrolled in this study. The patients with acute hydrocephalus after interventional embolization were randomly divided into observation group (n = 98) and control group (n = 98) without acute hydrocephalus. Statistics of their gender, age, smoking history, history of alcohol consumption, history of hypertension, Hunt-Hess classification, aneurysm location, ventricular hemorrhage, early waist drainage. Pearson single factor test, multivariate logistic regression analysis to determine the independent influencing factors of acute hydrocephalus. Results Univariate analysis showed that there was a significant correlation between Hunt-Hess grade, ventricular hemorrhage, early waist drainage and acute hydrocephalus (P <0.05). Multivariate regression analysis showed that the Hunt-Hess grade was independent of postoperative acute hydrocephalus The risk factors (partial regression coefficient of 2.677, OR = 14.542, 95% CI = 1.208 ~ 41.31), early drainage for the independent postoperative acute hydrocephalus protection factor (partial regression coefficient -3.201, OR = 0.041,95% CI = 0.003 ~ 0.412). Conclusions Hunt-Hess classification is an independent risk factor for acute hydrocephalus after embolization of intracranial aneurysm rupture. Early drainage of the waist can help prevent acute hydrocephalus.