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本院近年共收治血管瘤伴血小板减少综合征(Kasabach-Merritt 综合征)患儿8例,均采用激素局部注射疗法,取得满意疗效。临床资料:本组8例,男2例,女6例,年龄:1天～6个月。部位:颈面部2例,四肢4例,躯干2例;血管瘤面积最大15 cm×12 cm,最小8 cm×8 cm;症状均为出生时体表巨大红色斑块,近期迅速增大、变硬,5例伴有全身广泛散在性出血点,血常规示血小板数(5.6～30)×10~9/L,凝血时间15′～40′不等。治疗方法:在检查无病毒、细菌感染的情况下,每日清晨以确炎舒松 A40mg+倍他米松磷酸钠5.26mg,用8号针头在血管瘤局部多方向均匀注射,连续3天,所有病例肿块迅速缩小,血小板数均上升致100×10~9/L 以上。
Our hospital in recent years were treated with hemangiomas with thrombocytopenia syndrome (Kasabach-Merritt syndrome) in 8 children, are using hormone local injection therapy, and achieved satisfactory results. Clinical data: The group of 8 patients, 2 males and 6 females, age: 1 day to 6 months. Parts: 2 cases of neck and face, 4 cases of limbs and 2 cases of trunk; the largest area of hemangioma was 15 cm × 12 cm and the smallest was 8 cm × 8 cm. The symptoms were both huge red patches at birth and rapidly increasing Hard, 5 cases were accompanied by a wide range of systemic scattered bleeding, blood showed platelet count (5.6 ~ 30) × 10 ~ 9 / L, clotting time ranging from 15 ’to 40’. Treatment: In the examination of virus-free, bacterial infections, the morning of every morning to do with arson A40mg + betamethasone sodium phosphate 5.26mg, with 8 needles in the hemangioma local multi-directional injection for 3 days, all cases Tumor rapidly narrowing, platelet count rose to 100 × 10 ~ 9 / L or more.