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目的 探讨睾丸肿瘤早期治疗和随访监测的合理措施 ,评价其远期疗效。方法 回顾总结了6 9例睾丸肿瘤患者临床资料和随访监测情况。结果 6 1例患者中位随访时间 10 .8年 ,Ⅰ期和Ⅱ～Ⅲ期患者无瘤生存率分别为 91.7% (44 / 48) ,38.5 % (5 / 13) ;总生存率为 96 .8% (46 / 48) ,5 3 .8% (7/ 13) ;7例死于肿瘤转移 ,其中 5例晚期肿瘤患者均在术后 1～ 3年内死亡。结论 ①早期睾丸肿瘤行根治性睾丸切除后辅以适当放疗或化疗 ,预后良好。睾丸肿瘤治疗后复发或失败多发生于术后 3年之内 ,远期复发较为少见。②成年后隐睾行睾丸固定对日后癌变保护作用有限。③胚胎癌、淋巴肉瘤、Ⅱ～Ⅲ期肿瘤血管及淋巴转移侵犯是睾丸肿瘤的高危因子 ,对此宜采取更为积极的治疗措施并进行严密随访。该类肿瘤预后欠佳
Objective To explore the reasonable measures of early treatment and follow-up monitoring of testicular tumors to evaluate their long-term efficacy. Methods The clinical data and follow-up monitoring of 69 patients with testicular cancer were reviewed. Results The median follow-up time was 10.1 years in 61 patients, with 91.7% (44/48) and 38.5% (5/13) of patients in stage I and II-III, respectively. The overall survival rate was 96%. 8 (46/48) and 53.8% (7/13), respectively. Seven patients died of tumor metastasis. Five patients with advanced tumors died one to three years after operation. Conclusion ① The early testicular tumors after radical orchiectomy with appropriate radiotherapy or chemotherapy, the prognosis is good. Testicular tumor recurrence or failure after treatment occurred more than 3 years after surgery, long-term recurrence is rare. ② adult cryptorchid testicular fixation for future cancer protection is limited. ③ embryonic carcinoma, lymphosarcoma, stage Ⅱ ~ Ⅲ tumor invasion of blood vessels and lymph nodes is a high risk factor for testicular cancer, which should take more aggressive treatment and follow-up closely. The prognosis of such tumors is not good