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目的 观察母牛分枝杆菌疫苗(即微卡苗)对机体体液免疫的影响。方法 测定PPD强阳性者注射微卡苗前、后12周,服异烟肼前、后血清IgG抗体OD值并进行对比分析。结果 注射微卡苗前、后12周血清抗体水平明显升高(P<0.01)阳性率由25%上升为80%。服药组、对照组抗体水平治疗前、后无差异。结论 注射微卡苗可提高机体的体液免疫水平,对于结核病的发生可能有预防效果,比服药更安全、易于控制。
Objective To observe the effect of Mycobacterium vaccae vaccine (micro-card seedling vaccine) on humoral immunity of the body. Methods Serum IgG antibody OD value before and after 12 weeks after inoculation of microcapsule seedlings with strong positive PPD was determined and compared. Results The level of serum antibody increased significantly (P <0.01) from 25% to 80% at the 12th week after injection. The medication group, the control group antibody levels before and after treatment no difference. Conclusion Injection of microcarrier vaccine can improve the level of body fluid immunity, which may have a preventive effect on the occurrence of tuberculosis and is safer and easier to control than medication.