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目的:探讨B超子宫内膜厚度、血清β-人绒毛膜促性腺激素(β-HCG)、雌二醇(E2)和孕酮(P)在异位妊娠早期诊断中的应用。方法:选取贺州市人民医院2007年1月～12月住院的疑似异位妊娠的152例孕妇,行B超检查测量子宫内膜厚度及测定血清β-HCG、E2、P值。结果:152例疑似异位妊娠孕妇子宫内膜厚度及血清β-HCG、E2及P值高于正常非妊娠者。宫内妊娠组子宫内膜厚度、β-HCG、E2及P值明显高于异位妊娠组(P<0.05);正常宫内妊娠组子宫内膜厚度、β-HCG及P值高于宫内妊娠流产组;正常宫内妊娠组与宫内妊娠流产组E2值均很高,异位妊娠组E2值低(P<0.05)。结论:血清β-HCG及孕酮值是确定妊娠的指标,但难以鉴别异位妊娠和尚未形成宫内孕囊的早早孕及宫内妊娠流产,结合子宫内膜厚度、血清β-HCG、E2、P值则能预测妊娠的着床部位,为防止误诊提供了一个有价值的临床早期诊断指标。
Objective: To investigate the application of B-endometrial thickness, serum β-human chorionic gonadotropin (β-HCG), estradiol (E2) and progesterone (P) in early diagnosis of ectopic pregnancy. Methods: A total of 152 pregnant women with suspected ectopic pregnancy hospitalized in Hezhou People ’s Hospital from January 2007 to December 2007 were enrolled. The thickness of endometrium was measured by B - mode ultrasound and the serum β - HCG, E2 and P levels were measured. Results: The thickness of endometrium and the serum levels of β-HCG, E2 and P in 152 suspected ectopic pregnant women were higher than those in normal non-pregnant women. The uterine endometrial thickness, β-HCG, E2 and P values in uterine pregnancy group were significantly higher than those in ectopic pregnancy group (P <0.05). The uterine endometrium thickness, β-HCG and P value in intrauterine pregnancy group were higher than those in intrauterine group E2 in normal pregnancy group and intrauterine pregnancy group were both high, E2 was lower in ectopic pregnancy group (P <0.05). Conclusion: Serum β-HCG and progesterone values are indicators of pregnancy, but it is difficult to distinguish ectopic pregnancy and intrauterine gestational sac of early pregnancy and intrauterine pregnancy miscarriage, combined with endometrial thickness, serum β-HCG, E2 , P value can predict the implantation site of pregnancy, in order to prevent misdiagnosis provides a valuable clinical early diagnosis.