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目的:探讨二甲双胍对2型糖尿病胰岛素抵抗的影响。方法:选取2015年1月至2015年5月我院收治的30例2型糖尿病胰岛素抵抗患者作为研究对象,将患者分为对照组和观察组,每组各15例,对照组采用安慰剂治疗,观察组采用二甲双胍治疗,观察二甲双胍对2型糖尿病胰岛素抵抗的治疗效果。结果:对照组患者治疗前后的空腹血糖、餐后2 h血糖、胰岛素使用剂量无明显变化。与治疗前相比,治疗后观察组患者的空腹血糖、餐后2 h血糖、胰岛素使用剂量明显减少(P<0.05)。结论:二甲双胍治疗2型糖尿病胰岛素抵抗具有良好效果。
Objective: To investigate the effect of metformin on insulin resistance in type 2 diabetes. Methods: From January 2015 to May 2015 in our hospital treated 30 cases of type 2 diabetic patients with insulin resistance as the research object, the patients were divided into control group and observation group, 15 cases in each group, the control group was treated with placebo , The observation group was treated with metformin to observe the effect of metformin on type 2 diabetes insulin resistance. Results: Before and after treatment, the fasting blood glucose, postprandial 2h blood glucose and insulin dosage did not change significantly in the control group. Compared with those before treatment, the fasting blood glucose, postprandial 2-hour postprandial blood glucose and insulin dosage of the observation group decreased significantly (P <0.05). Conclusion: Metformin treatment of type 2 diabetes with insulin resistance has good effect.