研究者运用表面化学、电化学和细胞培养等生化方法 ,以及 IR、XRF、UV等谱学和电子微束手段 ,通过对主要 6类不同形态矿物粉尘的特征、表面官能团和活性位分析以及电化学、溶解、毒性研究等 ,提出了表面介体的概念并初步验证了它的存在 ;从表面官能团、表面综合性状探讨了矿物纤维材料的表面化学活性—生物活性—生物持久性—生物毒性—环境安全性 ;提出界 /膜体系来研究矿物产生生物毒性的过程和所依存的条件 ;对矿物粉尘在 Gamble溶液、血清与生物大分子、人体有机酸、氨基酸、维生素中以及动物体内行为的研究 ,进一步阐明了在氨基酸 /蛋白质 /功能膜以及含有外露蛋白质的其它有机体单元中粉尘的溶解、反应、络合与破坏 ,粉尘中的硅成分在体内的残留、溶解、运移方式 ,选择性吸附体液中的脂 -醇类物质、红细胞及其残片 ,粉尘与体内物质交换及免疫细胞的相互作用过程 ;提供了降低粉尘毒性的处理方式 Researchers using surface chemistry, electrochemical and cell culture biochemical methods, as well as IR, XRF, UV spectroscopy and electron microbeam means, the main six kinds of different forms of mineral dust characteristics, surface functional groups and active sites analysis and electricity Chemical, dissolution and toxicity, the concept of surface mediator was proposed and its existence was preliminarily verified. The surface chemical activity, biological activity, biological persistence and biological toxicity of mineral fiber material were discussed based on the surface functional groups and the surface comprehensive properties. Environmental safety; Proposed sector / membrane system to study the process of biological toxicity and dependent on the conditions of mineral dust in Gamble solution, serum and biological macromolecules, human organic acids, amino acids, vitamins and animal behavior in vivo studies , Further elucidates the dissolution, reaction, complexation and destruction of dust in the amino acid / protein / functional membrane and other organic unit containing the exposed protein, the residual, dissolution and transport modes of the silicon in dust, the selective adsorption Fat-alcoholic substances in body fluids, red blood cells and their debris, dust and body matter Exchange and immune cell interaction processes; Providing reduce dust treatment toxicity