迄今为止,尚未观察到胃癌细胞染色体恒定的特异性改变。我们对两例原发性胃癌患者的癌细胞进行了细胞遗传学分析。一例诊断为低分化腺癌,有浆膜浸润和局部淋巴结转移。细胞经短期培养5天收获,G显带,对41个可分析的中期相进行核型分析。另一例为由原发性肿瘤组织建立的胃腺癌细胞系(SC—M1),G显带,分析50个中期相。 To date, constant changes in the specificity of chromosomes in gastric cancer cells have not been observed. We performed cytogenetic analysis of cancer cells in two patients with primary gastric cancer. One case was diagnosed as a poorly differentiated adenocarcinoma with serosal infiltration and local lymph node metastasis. The cells were harvested by short-term culture for 5 days, G banding, and karyotype analysis was performed on 41 analyzable metaphases. Another example is a gastric adenocarcinoma cell line (SC-M1) established by primary tumor tissue, G banding, and analysis of 50 metaphases.