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ｂｃｌ２是一类与细胞凋亡相关的癌基因，其过度表达所致细胞凋亡受抑制是肿瘤发生的重要基础，并增加肿瘤细胞对放疗和化疗的抵抗性。本试验以脂质体为载体，对ｂｃｌ２ｍＲＮＡ翻译起始部位的反义寡核苷酸导入小细胞肺癌（ＳＣＬＣ）细胞，探讨其对ＳＣＬＣ细胞ｂｃ...
Bcl 2 is a type of oncogene associated with apoptosis. Inhibition of apoptosis by over-expression of bcl-2 is an important basis for tumorigenesis and increases the resistance of tumor cells to radiotherapy and chemotherapy. In this study, liposomes as a carrier, the antisense oligonucleotide of bcl 2mRNA translation initiation site into small cell lung cancer (SCLC) cells, to explore its SCLC cell bc ...