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免疫球蛋白超家族类细胞粘附分子(IgSF-CAMs)是一类跨膜糖蛋白,与肿瘤侵袭转移关系密切。本文概述了IgSF类细胞粘附分子的种类以及它们与头颈部恶性肿瘤侵袭转移的关系,对阐明肿瘤侵袭转移机制、评价肿瘤的转移能力以及患者的预后具有重要意义。
Immunoglobulin superfamily cell adhesion molecule (IgSF-CAMs) is a type of transmembrane glycoprotein, which is closely related to tumor invasion and metastasis. This article summarizes the types of IgSF cell adhesion molecules and the relationship between them and the invasion and metastasis of head and neck malignant tumors. It is of great significance to clarify the mechanism of tumor invasion and metastasis, evaluate the metastasis of tumor and the prognosis of patients.