作者检测了25例原发性肝癌、非癌肝组织以及外周血中豌豆凝集素结合型甲胎蛋白(AFP-R-P)含量,分别为41±26％、30±27％和36±25％。≤3cm、包膜完整、没有向周围肝组织浸润性生长、无血管癌栓的肝癌组织中AFP-R-P含量较低,患者术后生存期较长。结果提示,AFP-R-P主要由恶性行为较高的肝癌细胞所分泌,它直接或经血路向周围肝组织弥散,同时进入外周血循环,使血清中AFP-R-P含量升高。 The authors detected 25 samples of primary liver cancer, non-cancerous liver tissue, and peripheral blood pea-lectin-associated alpha-fetoprotein (AFP-R-P) levels of 41±26%, 30±27%, and 36±25%, respectively. AFP-R-P levels were lower in HCC tissues with ≤3 cm in size, complete encapsulation, invasive growth of peripheral liver tissue, and no vascular tumor embolus, and the patients had longer postoperative survival periods. The results suggest that AFP-R-P is mainly secreted by hepatocarcinoma cells with high malignant behavior. It diffuses directly or through the bloodstream to the surrounding liver tissue and enters the peripheral blood circulation at the same time, which increases the serum AFP-R-P level.