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目的:观察鞘内注射以及放脑脊液连续减压治疗结核性脑膜炎的临床疗效。方法:对照组25例单纯正规抗痨治疗,治疗组25例在正规抗痨基础上加用鞘内注射以及放脑脊液连续减压治疗,比较两组疗效。结果:治疗组治疗有效率(76%)明显高于对照组(48%),病死率(4%)低于对照组(20%)。结论:鞘内注射异烟肼和地塞米松以及放脑脊液连续减压治疗可减轻症状,减少并发症发生,提高好转率,缩短住院时间,降低病死率。
Objective: To observe the clinical effects of intrathecal injection and sequential decompression of cerebrospinal fluid in the treatment of tuberculous meningitis. Methods: 25 patients in the control group were treated with pure anti-tuberculosis therapy. Twenty-five patients in the treatment group received intrathecal injection and continuous decompression of cerebrospinal fluid on the basis of regular anti-tuberculosis. The curative effect was compared between the two groups. Results: The effective rate (76%) in the treatment group was significantly higher than that in the control group (48%), and the mortality rate (4%) was lower than that in the control group (20%). Conclusion: The intrathecal injections of isoniazid and dexamethasone and cerebrospinal fluid can relieve the symptoms, reduce the incidence of complications, improve the rate of turnover, shorten the length of hospital stay and reduce the mortality rate.