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目的探讨息肉状脉络膜血管病变(PCV)患者的流行病学特点及临床表现特征。方法回顾性分析2011年8月至2015年1月收治的PCV患者87例(107眼),分析其流行病学特点、眼底检查、荧光素钠眼底血管造影(FFA)及吲哚菁绿眼底血管造影(ICGA)检查资料。结果 87例(107眼)PCV患者中,男性占57.5%(50例),单眼受累占77.0%(67例)。41~92岁,平均(66.4±9.4)岁。51.4%(55眼)见出血性视网膜色素上皮层脱离(PED),45.8%(49眼)见视网膜下橘红色隆起改变。77.6%(83眼)息肉状病灶位于黄斑区,息肉状病灶1~8个,平均(2.71±1.79)个,单灶性与多灶性息肉状病灶中最大者平均面积分别为(0.52±0.35)mm2和(0.49±0.37)mm2。结论 PCV患者多见于男性,以单眼发病为主,临床表现为好发于黄斑区的出血性PED及视网膜下橘红色隆起改变,单灶性息状病的平均面积大于息肉状病灶中最大者的平均面积。
Objective To investigate the epidemiological characteristics and clinical features of patients with polypoidal choroidal vasculopathy (PCV). Methods A retrospective analysis was performed on 87 patients (107 eyes) with PCV admitted from August 2011 to January 2015. The epidemiological characteristics, fundus examination, fluorescein sodium fundus angiography (FFA) and indocyanine green fundus Contrast (ICGA) examination data. Results 87 (107 eyes) PCV patients, 57.5% of men (50 cases), monocular involvement accounted for 77.0% (67 cases). 41 to 92 years old, with an average of 66.4 ± 9.4 years. Hemorrhagic retinal pigment epithelial detachment (PED) occurred in 51.4% (55 eyes), and subtle retina orange folds in 45.8% (49 eyes). The average number of polypoid lesions in the macular area and polypoid lesions was 1 to 8 with an average of 2.71 ± 1.79. The average area of the largest single polypoid lesions was (0.52 ± 0.35) ) mm2 and (0.49 ± 0.37) mm2. Conclusions PCV is more common in men than in monocular disease. The clinical manifestations are hemorrhagic PEDs which occur in the macular area and the subretinal orange-red bulge. The average area of single-foci is larger than that of the largest polypoid lesion Average area.