围产期是人生经历中最剧烈的变化时期。在此期间所有系统、器官、组织都需进行适应性变化,尤以呼吸系统为最。胎儿要从宫内液态环境转向宫外气态环境;从液一液间转为液一气间的气体交换;司呼吸的器官也从胎盘转为肺。这一复杂多变的生理过程影响了呼吸系统的稳定性,致使该时期的发病率和死亡率都较其他时期为高。为此,有关呼吸机制的研究成为儿科、产科临床工作者共同关注的重要课题。本文就有关研究的进展综述如下。 Perinatal period is the most dramatic period of change in life experience. During this period all systems, organs, organizations need to adapt to changes, especially the respiratory system is the most. Fetal from the intrauterine liquid environment to the ectopic gaseous environment; from liquid to liquid gas exchange between the gas; Secretary breathing organs from the placenta to the lungs. This complex and changeable physiological process affected the stability of the respiratory system, resulting in higher morbidity and mortality during this period than in other periods. Therefore, the research on respiratory mechanism has become an important issue of common concern to pediatric and obstetric clinicians. This article reviews the progress of the research are as follows.