随着肿瘤免疫学以及基因工程的发展,用疫苗引发机体自身杀伤肿瘤的主动特异性免疫疗法治疗肿瘤成为当今肿瘤生物治疗的新热点。本文就颅内最常见肿瘤———神经胶质瘤的主动特异性免疫疗法在细胞疫苗、分子疫苗、核酸疫苗三方面的进展进行综述。 With the development of tumor immunology and genetic engineering, the treatment of tumors with vaccines that trigger the body’s own tumor-killing active-specific immunotherapy has become a new hot spot in tumor biological treatment. In this paper, the most common intracranial tumor --- glioma active specific immunotherapy in cell vaccine, molecular vaccine, nucleic acid vaccine in three aspects are reviewed.