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目的观察小剂量罗哌卡因复合舒芬太尼腰硬联合麻醉用于无痛分娩的疗效。方法将360例无痛分娩的产妇随机分为A、B、C 3组,每组120例。3组患者均采用腰硬联合麻醉方式,此外,A组仅给予舒芬太尼,B组给予罗哌卡因,C组给予小剂量盐酸罗哌卡因复合舒芬太尼,对比3组产前(T0)、活跃期(T1),第二产程(T2)、第三产程(T3)的疼痛程度评分(VAS),对比3组新生儿体质量、Apgar评分和不良反应发生率。结果 C组T1、T2及T3时间点的VAS评分和产妇不良反应发生率均低于A、B组,而C组的新生儿体质量及Apgar评分明显高于A、B组,差异均有统计学意义(P<0.05)。A组、B组各时点VAS评分、新生儿体质量、Apgar评分和不良反应发生率差异均无统计学意义(P>0.05)。结论小剂量罗哌卡因复合舒芬太尼腰硬联合麻醉用于分娩镇痛疗效良好。
Objective To observe the efficacy of low-dose ropivacaine combined with sufentanil combined with spinal anesthesia for painless childbirth. Methods 360 cases of painless childbirth were randomly divided into A, B and C groups, 120 cases in each group. Three groups of patients were treated by combined spinal and epidural anesthesia. In addition, group A received only sufentanil, group B received ropivacaine, group C received low dose ropivacaine hydrochloride and sufentanil, (T0), active stage (T1), second stage (T2) and third stage (T3), and compared the neonatal weight, Apgar score and incidence of adverse reactions. Results The VAS score and maternal adverse reaction rate in group C at T1, T2 and T3 were lower than those in group A and B, while the newborn’s weight and Apgar score in group C were significantly higher than those in group A and B Significance (P <0.05). There was no significant difference in VAS score, neonatal body weight, Apgar score and incidence of adverse reactions between groups A and B (P> 0.05). Conclusion Small doses of ropivacaine combined with sufentanil combined with spinal and epidural anesthesia is effective in labor analgesia.