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目的 观察中医辨证论治对卧床模拟失重引起的主要证型的辨证论治效果。 方法 将被试者随机分成中药组(ZH组)和对照组(CO组)各5人,头低位-6°,卧床21 d。依据预先同样卧床条件下辨证的主要证型采用益气、养阴、活血、健脾等方法对ZH组进行论治,同时辨证对证型评分和检测对应的生理生化指标。 结果 ZH组无论中医证型或对应的生理生化指标(尿量、血浆皮质醇、睾酮、全血黏度、红细胞变形性、立位耐力、尿木糖排泄率)都能维持卧床前水平(P<0 05)或轻度改变,CO组改变明显。 结论 卧床模拟失重21 d引起的肾阴虚、血瘀、脾气虚等主要证型,经采用本方初步显示较好的改善效果,其中改善肾阴虚、血瘀证较明显。
Objective To observe the syndrome differentiation of traditional Chinese medicine treatment of bed-ridden simulated weightlessness caused by the main syndrome differentiation effect. Methods Subjects were randomly divided into five groups: Chinese medicine group (ZH group) and control group (CO group) with head low -6 ° and bed rest 21 days. On the basis of the same cardinal syndromes under the same bed conditions, syndrome differentiation, nourishing yin, promoting blood circulation and invigorating the spleen were used to treat ZH group. At the same time, the syndrome differentiation and the physiological and biochemical indexes were tested. Results The ZH group could maintain the level of bedridden regardless of syndrome type of TCM or the corresponding physiological and biochemical indexes (urine output, plasma cortisol, testosterone, whole blood viscosity, erythrocyte deformability, standing endurance and urinary excretion rate of urine) (P < 0 05) or slightly changed, CO group changed significantly. Conclusion The main syndrome types of kidney-yin deficiency, blood stasis and spleen-qi deficiency caused by bed-ridden simulated weight loss for 21 d have shown preliminary improvement by using this prescription, of which the improvement of kidney-yin deficiency and blood stasis syndrome are obvious.