论文部分内容阅读
目的:探究艾迪注射液联合顺铂、5-氟尿嘧啶治疗胃癌的临床疗效。方法:选取中山市人民医院2014年1月至2016年12月48例胃癌患者作为研究对象,通过随机数字表法将其分为对照组与观察组,每组24例。对照组采用顺铂联合5-氟尿嘧啶进行治疗,观察组则在对照组的基础上联合艾迪注射液进行治疗。两组患者均以21 d为1个周期,两个周期为1个疗程,连续治疗两个周期后对于两组患者的临床效果以及不良反应进行记录,比较两组患者的CD4/CD8水平。结果:观察组的总有效率高于对照组,组间比较,差异无统计学意义(P>0.05),观察组的不良反应情况优于对照组,组间比较,差异具有统计学意义(P<0.05)。观察组CD4/CD8的数值明显低于对照组,组间比较,差异具有统计学意义(P<0.05)。结论:艾迪注射液联合顺铂、5-氟尿嘧啶对于胃癌进行治疗不仅能够调节患者的免疫功能,还能够减少患者的不良反应。
Objective: To investigate the clinical efficacy of Aidi injection combined with cisplatin and 5-fluorouracil in the treatment of gastric cancer. Methods: Forty-eight patients with gastric cancer from January 2014 to December 2016 in Zhongshan People’s Hospital were enrolled and divided into control group and observation group by random number table method, with 24 cases in each group. The control group was treated with cisplatin plus 5-fluorouracil. The observation group was treated with Aidi Injection on the basis of the control group. Two groups of patients were 21 days for a cycle of two cycles for a course of treatment for two cycles of continuous treatment for both groups of patients with clinical effects and adverse reactions were recorded to compare the two groups of patients with CD4 / CD8 levels. Results: The total effective rate in the observation group was higher than that in the control group. There was no significant difference between the two groups (P> 0.05). Adverse reactions in the observation group were better than those in the control group. The differences were statistically significant (P <0.05). The values of CD4 / CD8 in the observation group were significantly lower than those in the control group. The differences between the two groups were statistically significant (P <0.05). Conclusion: Aidi injection combined with cisplatin and 5-fluorouracil can not only regulate the immune function of patients but also reduce the adverse reactions of patients.