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目的:分析比较临床药师干预前后我院剖宫产预防用抗菌药情况。方法:分别统计我院2012年5月(干预前)57例和7月(干预后)56例剖宫产手术患者预防用抗菌药使用情况,评价用药合理性。结果:干预后,选择药物合理性从33.3%上升至83.9%(P<0.01),联合用药率从26.3%下降至10.7%(P<0.05),预防用药疗程从4.3 d下降至3.4 d(P<0.01),用法用量合理性也有了明显改善(P<0.05)。结论:临床药师通过药学干预,促进剖宫产术预防用抗菌药的合理使用。
Objective: To compare and analyze the situation of antibacterial drugs for prevention of cesarean section in our hospital before and after the intervention of clinical pharmacists. Methods: The use of prophylactic antimicrobials in 57 cases of cesarean section in May 2012 (before intervention) and 56 cases of cesarean in July (after intervention) in our hospital were respectively counted to evaluate the rationality of medication. Results: After the intervention, the rationality of selected drugs increased from 33.3% to 83.9% (P <0.01), and the combination rate dropped from 26.3% to 10.7% (P <0.05), while the course of prophylaxis decreased from 4.3 days to 3.4 days <0.01), and the usage ration ration has also been significantly improved (P <0.05). Conclusion: Pharmacists through clinical pharmacists to promote the rational use of antimicrobial agents for cesarean section prevention.