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比较Ｖｅｒａｐａｍｉｌ和Ｐｒｏｐｒａｎｏｌｏｌ对患有胰岛素非依赖型糖尿病及轻度至中度高血压的透析患者的血糖和物质代谢的影响。方法：４６例患有非胰岛素依赖型糖尿病及轻度至中度高血压的透析患者，为德国福尔达市ＫｆＨ血透中心和柏林ＫｆＨ血透中心的透析病人。分别经Ｖｅｒａｐａｍｉｌ和Ｐｒｏｐｒａｎｏｌｏｌ治疗三个月后测空腹血糖、血红蛋白Ａ１ｃ、果酸、胰岛素、胆固醇和甘油三脂，同时记录透析前心率和血压。结果：Ｖｅｒａｐａｍｉｌ对血糖及物质代谢无不良影响，Ｐｒｏｐｒａｎｏｌｏｌ可引起血糖、果酸和血红蛋白Ａ１ｃ升高。结论：在糖尿病透析患者，Ｐｒｏｐｒａｎｏｌｏｌ具有引起和／或加重小动脉血管病病以及脑血管意外的危险性
To compare the effects of Verapamil and Propranolol on blood glucose and substance metabolism in dialysis patients with insulin-independent diabetes and mild to moderate hypertension. Methods: Forty-six patients with non-insulin-dependent diabetes mellitus and those with mild to moderate hypertension were dialysis patients at the KfH hemodialysis center in Folda, Germany and the KfH hemodialysis center in Berlin. Fasting blood glucose, hemoglobin A1c, acid, insulin, cholesterol, and triglyceride were measured three months after treatment with Verapamil and Propranolol respectively. Heart rate and blood pressure were recorded before dialysis. RESULTS: Verapamil had no adverse effect on blood glucose and substance metabolism. Propranolol caused an increase in blood glucose, acid and hemoglobin A1c. CONCLUSIONS: Propranolol has a risk of causing and / or exacerbating arteriolar vascular disease and cerebrovascular accidents in diabetic dialysis patients