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目的:对应用亚麻醉剂量氯氨酮在小儿骨科手术硬膜外麻醉与神经阻滞辅助用药的安全性进行研究探讨。方法:将72例进行骨科手术的患儿随机分为治疗组与对照组,治疗组36例患儿在手术时辅以亚麻醉剂量氯氨酮,对照组36例患儿不辅以任何措施。结果:治疗组患儿麻醉中安静未诉不适的有效率为91.7%,对照组患儿麻醉中安静未诉不适的有效率为52.8%,两组相比具有显著差异(P<0.05)。结论:亚麻醉剂量氯氨酮作为小儿骨科手术硬膜外麻醉与神经阻滞辅助用药,可以对患儿的紧张焦虑情绪进行有效安全的改善,增强患儿对手术引起不适的耐受。
Objective: To study the safety of sub-anesthetic ketamine in pediatric orthopedic surgery and neurological blockade adjuvant. Methods: Seventy-two children undergoing orthopedic surgery were randomly divided into treatment group and control group. 36 patients in the treatment group were anesthetized with ketamine during operation and 36 patients in the control group were supplemented with any measures. Results: The effective rate of anesthesia in the treatment group was 91.7%, while that of the control group was 52.8%. There was a significant difference between the two groups (P <0.05). CONCLUSION: The sub-anesthetic dose of ketamine acts as an adjunct to epidural anesthesia and nerve block in pediatric orthopedic surgery, which can effectively and safely improve the anxiety and anxiety in children and enhance the patient’s tolerance to surgery-induced discomfort.