头孢双硫唑甲氧(cefotetan,商品名Apatef,每瓶含1g 或2g)是第三代先锋霉素,抗菌谱类似于头孢甲氧霉素(cefo-xitin)。在体外显示广谱抗需氧菌和厌氧菌作用,但对大多数假单孢菌属、粪链球菌、不动杆菌属和耐新青霉素Ⅰ的金黄色葡萄球菌无作用。该药已被批准用于治疗成人泌尿道、下呼吸道、皮肤、软组织、腹部感染和脓毒血症,也可用于预防下泌尿道外科手术病人的术后感 Cefotetan (cefotetan, trade name Apatef, bottle containing 1g or 2g) is the third generation of cephalosporins, antibacterial spectrum similar to cefomycin (cefo-xitin). In vitro broad-spectrum anti-aerobic and anaerobic bacteria, but most of Pseudomonas, Streptococcus faecalis, Acinetobacter and resistant to new penicillin Ⅰ Staphylococcus aureus no effect. The drug has been approved for the treatment of adult urinary tract, lower respiratory tract, skin, soft tissue, abdominal infections and sepsis, and can also be used to prevent postoperative urinary tract surgery patients