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目的：筛选青霉素Ｖ钾分散片的处方．建立青霉素Ｖ钾分散片的含量测定方法。方法：采用均匀设计法筛选处方；紫外分析法测定含量。结果：青霉素 Ｖ钾分散片崩解时限４５～９０ｓ，Ｔ５０ １．０９ｍｉｎ，Ｔｄ ２．０７ｍｉｎ；紫外测定回收率９７．５４％。结论：按本文处方生产的青霉素Ｖ钾分散片质量符合英国药典对分散片的要求；紫外方法快速、简便，准确度较高。
Objective: Screening penicillin V potassium dispersible tablets prescription. Establishment of penicillin V potassium dispersible tablets content determination. Methods: uniform design method for screening prescriptions; UV analysis of content. Results: The disintegration time of penicillin V potassium dispersible tablet was 45 ~ 90s, T50 1.09min, Td 2.07min; UV detection recovery 97.54%. Conclusion: The quality of penicillin V potassium dispersible tablets produced by this prescription conforms to the requirements of the British Pharmacopoeia for dispersible tablets. The UV method is rapid, simple and accurate.