卒中后抑郁(post-stroke depression,PSD)是脑卒中后最常见的神经精神并发症之一,可严重影响脑卒中患者神经功能、认知功能及日常生活能力的改善,增加病死率和脑卒中复发的风险,降低患者回归社会的比例,给个人、家庭及社会带来很大负担。近年来PSD成为周内外学者研究的热点,笔者就其中西医发病机制,综述如下。 Post-stroke depression (PSD) is one of the most common neuropsychiatric complications after stroke, which can seriously affect the improvement of neurological function, cognitive function and daily living ability in patients with stroke, and increase the mortality and stroke The risk of relapse reduces the proportion of patients returning to society and places a heavy burden on individuals, families and the community. In recent years, PSD has become a hot spot in the study of scholars both inside and outside of China. The author has summarized the pathogenesis of these diseases as follows.