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目的了解支气管类癌的临床生物学特性,探讨合理的术式及综合治疗方法。方法对16例支气管类癌外科治疗结果进行综合分析。结果支气管类癌在临床上与一般肺癌相比无特征性表现。组织来源虽与小细胞未分化癌都起源于支气管黏膜神经内分泌细胞,因临床特点不同应将其分开为另一类。16例均予手术治疗。全肺切除3例,肺叶切除8例,双肺叶切除2例,袖切2例,探查1例。典型类癌11例,有3例纵隔淋巴结转移;不典型类癌5例,有2例纵隔淋巴结转移。全组病例进行2~18年随访,典型类癌与不典型类癌有明显差异。结论手术是治疗支气管类癌的主要手段。术式应根据患者年龄及肺功能状况及肿瘤位置、大小等因素来综合考虑。术前放射治疗对提高手术切除率有一定效果。
Objective To understand the clinical biological characteristics of bronchial carcinoid and explore reasonable surgical methods and comprehensive treatment. Methods A total of 16 cases of bronchial carcinoid surgical treatment results were analyzed. Bronchoid carcinoid in clinical and general lung cancer compared to no characteristic performance. Although the source of tissue and small cell undifferentiated carcinoma originated in bronchial mucosal neuroendocrine cells, due to different clinical features should be separated into another class. 16 cases were treated surgically. Total pneumonectomy in 3 cases, lobectomy in 8 cases, double lobectomy in 2 cases, sleeve cut in 2 cases, exploration in 1 case. Typical carcinoid in 11 cases, 3 cases of mediastinal lymph node metastasis; 5 cases of atypical carcinoid, 2 cases of mediastinal lymph node metastasis. All patients were followed up for 2 to 18 years, with typical carcinoid and atypical carcinoid significant differences. Conclusion Surgery is the main treatment of bronchial carcinoid. Surgery should be based on the patient’s age and lung function status and tumor location, size and other factors to be considered. Preoperative radiotherapy to improve the surgical resection rate has a certain effect.