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目的探讨热毒宁治疗老年呼吸机相关性肺炎的临床效果。方法选取2013年2月至2015年2月符合诊断标准的呼吸机相关性肺炎老年患者98例,依据治疗方案分为常规组和热毒宁组,每组49例。比较两组疗效。结果热毒宁组治疗后体温、白细胞计数(WBC)和胸部X线评分及血氧饱和度优于常规组,差异有统计学意义(P<0.05)。热毒宁组治疗后血浆白细胞介素(IL)-6、白细胞介素(IL)-8、白细胞介素(IL)-1β、肿瘤坏死因子(TNF-α)水平低于常规组,差异有统计学意义(P<0.05)。结论热毒宁辅助治疗老年呼吸机相关性肺炎效果显著,能够显著缓解患者临床症状,抑制炎症因子,值得推广。
Objective To investigate the clinical effect of Renduining in the treatment of senile ventilator-associated pneumonia. Methods A total of 98 senile patients with ventilator-associated pneumonia who met the diagnostic criteria from February 2013 to February 2015 were divided into two groups according to the treatment regimen: conventional group and reifuidine group, with 49 cases in each group. Compare the two groups curative effect. Results The body temperature, white blood cell count (WBC), chest X-ray score and oxygen saturation in the treatment group were better than those in the conventional group (P <0.05). The levels of plasma IL-6, IL-8, IL-1β and TNF-α in Reduining group were lower than those in the conventional group Statistical significance (P <0.05). Conclusion Renduining adjuvant treatment of elderly ventilator-associated pneumonia is significant, can significantly alleviate the clinical symptoms and suppress inflammatory factors, it is worth promoting.