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目的:观察自拟益肺活血方联合西药治疗小儿支气管哮喘急性发作的临床疗效。方法:将102例患儿随机分为观察组52例与对照组50例,2组均予抗炎、解痉等常规对症疗法,对照组在此基础上使用舒利迭沙美特罗替卡粉吸入剂,观察组在对照组基础上加服自拟益肺活血方,2组均治疗14天,对比2组治疗后的中医证候积分、临床疗效与不良反应发生情况。结果:2组患儿治疗14天后,观察组控制显效率高于对照组(P<0.05);2组总有效率比较,差异无显著性意义(P>0.05)。治疗14天后,中医证候积分观察组为(7.7±2.0)分,对照组为(10.4±2.8)分,2组比较,差异有显著性意义(P<0.05)。不良反应发生率观察组为38.5%,对照组为26.0%,2组比较,差异无显著性意义(P>0.05)。结论:在常规对症疗法基础上,采用益肺活血方联合舒利迭沙美特罗替卡粉吸入剂治疗小儿支气管哮喘急性发作,较单纯采用西药能进一步提高临床疗效,较为安全可靠。
Objective: To observe the clinical efficacy of Yifei Huoxue Recipe combined with western medicine in the treatment of acute attack of bronchial asthma in children. Methods: A total of 102 children were randomly divided into observation group (n = 52) and control group (n = 50). The two groups were given conventional anti-inflammatory and antispasmodic symptomatic therapy. The control group was treated with salmeterol salmeterol Inhaler and observation group were given self-made Yifeihuoxue prescription on the basis of the control group. Both groups were treated for 14 days. The TCM syndrome scores, clinical efficacy and adverse reactions were compared between the two groups after treatment. Results: After 14 days of treatment, the effective rate of control in observation group was significantly higher than that in control group (P <0.05). There was no significant difference in total effective rate between the two groups (P> 0.05). After 14 days of treatment, the TCM syndrome score was (7.7 ± 2.0) points in the observation group and (10.4 ± 2.8) points in the control group. There was significant difference between the two groups (P <0.05). The incidence of adverse reactions was 38.5% in the observation group and 26.0% in the control group. There was no significant difference between the two groups (P> 0.05). Conclusion: On the basis of conventional symptomatic therapy, Yifeihuoxue prescription combined with Salmeterol salmeterol powder inhalation is effective in treating acute attack of bronchial asthma in children, which is more safe and reliable than using western medicine alone.