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醋丁酰心安(acebutolol)是一种新的心脏选择性β—肾上腺素能拮抗剂,具有象心得安的所谓“奎尼丁样”的细胞膜稳定作用。本文报告一组频繁室性早搏(PVC)门诊患者短期使用醋丁酰心安的结果。患者男11例,女1例。平均年龄56岁(46～67岁)。8例为冠心病,其中5例曾患过心肌梗塞,4例有过心绞痛,2例轻度心脏增大伴代偿性充血性心力衰竭;1例为无充血性心力衰竭的心肌病;3例原因未明的无症状性PVC。对照期24小时心电图监护,均显示室性早搏平均多于1次/分钟。研究前停
Acebutolol, a new cardioselective β-adrenergic antagonist, has a potent so-called “quinidine-like” membrane-stabilizing effect. This article reports the results of short-term use of ambrisentan in a group of patients with frequent ventricular premature beings (PVC). There were 11 males and 1 females. The average age of 56 years (46 to 67 years old). 8 cases were coronary heart disease, including 5 cases of myocardial infarction, 4 cases of angina pectoris, 2 cases of mild heart enlargement with compensatory congestive heart failure, 1 case of cardiomyopathy without congestive heart failure, 3 cases Unexplained asymptomatic PVC. Control 24-hour ECG monitoring, both showed premature ventricular contractions average more than 1 time / minute. Stop before the study